今天是:2017年11月20日 星期一 农历十月初三
董琳 教授(博士生导师)
作者:佚名  来源:  发布时间:2017年07月09日  点击/评论:11858/0

董琳  教授 博士生导师

联系方式

电话:028-85503538

E-mail: donglinscu@aliyun.com

成都市人民南路三段17# 四川大学华西药学院,610041


简历

1994-1998 郑州大学化学系,化学专业,理学学士

2001-2006 中国科学院成都有机化学研究所,有机化学专业,硕博连读,师从龚流柱教授

2006-2009 澳大利亚昆士兰大学化学系,博士后,师从Craig M. Williams教授

2009-2011 新加坡科技研究局化学与工程科学研究院,研究科学家,师从著名化学家K. C. Nicolaou 教授

2011-2016 四川大学华西药学院,副教授

2016-至今 四川大学华西药学院,教授


 

获奖情况

12012 四川省引进海外高层次人才“百人计划”(现为四川省千人计划),四川省特聘专家

22012 四川大学优秀青年骨干教师奖励

32014 大学生课外科技实践活动优秀指导教师

42016 四川大学唐立新优秀学者奖

 

研究方向

<!--[if !supportLists]-->1、有机合成方法学研究

2、天然产物与药物合成

 

科研项目及成果

12013-2015  国家自然科学基金-青年基金

22016-2019  国家自然科学基金-面上项目

 

发表论文

[1]  Liu, C.-F.; Zhang, G.-T.; Sun, J.-S.; Dong, L.*, “Access to π-conjugated azaindole derivatives via rhodium(III)-catalyzed cascade reaction of azaindoles and diazo compounds”, Org. Biomol. Chem. 2017, 15, 2902–2905.

[2]  Xia, Y.-Q.; Dong, L.*, “Ruthenium(II)-Catalyzed Indolo[2,1-a]isoquinolines Synthesis by Tandem C?H Allylation and Oxidative Cyclization of 2-Phenylindoles with Allyl Carbonates”, Org. Lett., 2017, 19, 2258?2261.

[3]  Zhang, G.-T.; Dong, L.*, “Synthesis of Polycyclic Amides via Tandem RhIII-Catalyzed C-H

Activation and Annulation from Dioxazolones and Alkynes”,  Asia. J. Org. Chem. 2017, 6, 812 – 816.

[4]  Wu, L.; Dong, L.*, “The application of Morita-Baylis-Hillman reaction: Synthetic studies on perophoramidine”, Tetrahedron 2017, 73, 3966-3972.

[5]  Li, S.-S.; Liu, C.-F.; Zhang, G.-T.; Xia, Y.-Q.; Li, W.-H.; Dong, L.*, “A Convenient One-Pot Route to Screw-Shaped [5]Azahelicenes via Rhodium(III)-Catalyzed Multiple C-H Bond Activation”,  Chem. Asia. J. 2017, 12, 415-418.

[6]  Li, S.-S.; Xia, Y.-Q.; Liu, C.-F.; Zhang, G.-T.; Su, F.; Zhang, X.-M.; Dong, L.*, “Diverse Reactivity in a Rhodium(III)-Catalyzed Vinylic sp2 C–H Bond Functionalization: Synthesis of Fused Polycyclic Heteroarenes or Conjugated Dienes”, Adv. Synth. Catal. 2016, 358(23), 3724 –3729.

[7] Lin, H.; Dong, L.*, “One-Pot Synthesis of Decahydropyrene via Tandem C?H Activation/Intramolecular Diels?Alder/1,3-Dipolar Cycloaddition”; Org. Lett., 2016, 18, 5524?5527.

[8] Li, S.-S.; Xia, Y.-Q.; Hu, F.-Z.; Liu, C.-F.; Su, F.; Dong, L.*, “IrIII-Catalyzed One-Pot Cascade ynthesis of Pentacyclic-Fused Carbazoles from Indoles and Diazoes”, Chem. Asia. J. 2016, 11, 3165 – 3168.

[9] Li, W.-H.; Wu, L.; Li, S.-S.; Liu, C.-F.; Zhang, G.-T.; Dong, L.*, “Rhodium-Catalyzed Hydrogen-Releasing ortho-Alkenylation of 7-Azaindoles”, Chem. Eur. J. 2016, 22(50), 17926– 17929.

[10] Zhu, Y.-Q.; Qin, L.; Song, Q.; Su, F.; Xu, Y.-J.; Dong, L.*, “Rhodium(III)-catalyzed ortho-alkenylation using a cyclic N-phosphoryl ketimine as the directing group”, Org. Biomol. Chem. 2016, 14, 9472–9475.

[11] Li, S.-S.; Wu, L.; Qin, L.; Zhu, Y.-Q.; Su, F.; Xu, Y.-J.; Dong, L.*, “Iridium(III)-Catalyzed Tandem [3 + 2] Annulation: Synthesis of Spirocyclic Phosphoramide Derivatives”, Org. Lett., 2016, 18 (17), 4214–4217.

[12] Li, S.-S.; Li, W.-H.; Zhang, G.-T.; Xia, Y.-Q.; Liu, C.-F.; Su, F.; Zhang, X.-M.; Dong, L.*, One-pot construction of fused polycyclic heteroarenes involving 7-azaindoles and α,β-unsaturated ketones”, Org. Biomol. Chem., 2016, 14, 7859–7863.

[13] Wang, C.-Q.; Zhang, W., Lin, H.; Su, F.; Dong, L.*, “Synthesis of Isoquinolinium Salts via Rh(III)-catalyzed Oxidative Annulation between Aldehyde Imines and Alkynes”, HETEROCYCLES, 2016, 929,1674-1686.

[14] Li, S.-S.; Lin, H.; Liu, C.-F.; Xia, Y.-Q.; Zhang, X.-M.; Dong, L.*, “Rhodium-Catalyzed Tandem Annulation Reactions of 7-Azaindoles with Electron-Deficient Olefins via Double C-H Activation”, Adv. Synth. Catal. 2016, 358, 1595 –1601.

[15] Li, S.-S.; Liu, C.-F.; Xia, Y.-Q.; Li, W.-H.; Zhang, G.-T.; Zhang, X.-M.; Dong, L.*, “A unique annulation of 7-azaindoles with alkenyl esters to produce π-conjugated 7-azaindole derivatives”, Org. Biomol. Chem., 2016, 14, 5214–5218.

[16] Li, S.-S.; Qin, L.; Dong, L.*, “Rhodium-catalyzed C–C coupling reactions via double C–H activation”, Org. Biomol. Chem., 2016,14, 4554-4570.

[17] Li, S.-S.; Wang, C.-Q.; Li, W.-H.; Zhang, X.-M.; Dong, L.*, “Rhodium-catalyzed selective oxidative coupling of 7-azaindoles”, Tetrahedron 2016, 72, 2581-2586.

[18] Zhang, W., Wang, C.-Q.; Lin, H.; Dong, L.*, Xu, Y.-J, “Synthesis of Mesoionic Isoquinolines by Rhodium(III)-Catalyzed C-H Activation”, Chem. Eur. J. 2016, 22, 907-910.

[19] Li, S.-S.; Wang, C.-Q.; Lin, H.; Zhang, X.-M.; Dong, L.*, “Rhodium(III)-catalyzed C–C coupling of 7-azaindoles with vinyl acetates and allyl acetates”, Org. Biomol. Chem., 2016, 14, 229–237.

[20] Zhu, Y.-Q.; Dong, L.*, “One-Pot Synthesis of Polysubstituted Spirofluorene?Indene via Ru(II)-Catalyzed [3 + 2] Annulation and Intramolecular Friedel?Crafts Cyclization”, J. Org. Chem. 2015, 80 (20), 9973?9979

[21] Lin, H.; Li, S.-S.; Dong, L.*, “Synthesis of indoles and polycyclic amides via ruthenium(II)-catalyzed C-H activation and annulation”, Org. Biomol. Chem. 2015, 13, 11228-11234

[22] Li, S.-S.; Wang, C.-Q.; Lin, H.; Zhang, X.-M.; Dong, L.*, “Rhodium(III)-Catalyzed Oxidative Annulation of 7?Azaindoles and Alkynes via Double C?H Activation” Org. Lett. 2015, 17, 3018-3021.

[23] Huang, J.-R.; Qin, L.; Zhu, Y.-Q.; Song, Q.; Dong, L.* “Multi-site Cyclization via Initial C-H Activation Using Rhodium(III) Catalyst: Rapid Assembly of Frameworks Containing Indoles and Indolins” Chem. Comm. 2015, 51, 2844-2847.

[24] Li, S.-S.; Lin, H.; Zhang, X.-M.; Dong, L.* “Ruthenium-Catalyzed Direct C3 Alkylation of Indoles with α,β-Unsaturated Ketones”, Org. Biomol. Chem. 2015, 13,1254-1263.

[25] Zhang, W.; Zhang, Q.-R.; Dong, L.* “Rhodium-catalyzed [2+2+2] cycloaddition reactions of terminal alkynes with N-sulfonyl ketimines”, Tetrahedron Letters 2015, 56, 546–548.

[26] Zhang, Q.-R.; Huang, J.-R.; Zhang, W.; Dong, L.* “Highly Functionalized Pyridines Synthesis from N-Sulfonyl Ketimines and Alkynes Using N-S Bond as an Internal Oxidant”, Org. Lett. 2014, 16, 1684-1687.

[27] Huang, J.-R.; Song, Q.; Zhu, Y.-Q.; Qin, L.; Qian, Z.-Y.; Dong, L.* “Rhodium(III)-Catalyzed Three-Component Reactions of Imines, Alkynes, and Aldehydes via C–H Activation”, Chem. Eur. J. 2014, 20, 16882-16886.

[28] Dong, L.*; Qu, C.-H.; Huang, J.-R.; Zhang, W.; Zhang, Q.-R.; Deng, J.-G. “Rhodium-catalyzed Spirocyclic Sultam Synthesis by [3+2] Annulation with Cyclic N-Sulfonyl Ketimines and Alkynes”, Chem. Eur. J. 2013, 19, 16537-16540.

[29] Dong, L.*; Huang, J.-R.; Qu, C.-H.; Zhang, Q.-R.; Zhang, W.; Han, B.; Peng, C.* “Rhodium(III)-catalyzed vinylic sp2 C–H bond functionalization: efficient synthesis of pyrido[1,2-α]-benzimidazoles and imidazo[1,2-α]pyridines”, Org. Biomol. Chem. 2013, 11, 6142–6149.

[30] Huang, J.-R.; Zhang, Q.-R.; Qu, C.-H.; Sun, X.-H.; Dong, L.* Chen. Y.-C.* “Rhodium(III)-Catalyzed Direct Selective C(5)-H Oxidative Annulations of 2-Substituted Imidazoles and Alkynes by Double C-H Activation”, Org. Lett. 2013, 15, 1878-1881.

[31] Huang, J.-R.; Dong, L.*; Han, B.; Peng, C.; Chen. Y.-C. “Synthesis of Aza-Fused Polycyclic Quinolines via Double C-H Bond Activations, Chem. Eur. J. 2012, 18, 8896-8898.




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