今天是:2017年11月20日 星期一 农历十月初三
卿勇 副教授 (硕士生导师)
作者:佚名  来源:  发布时间:2016年02月11日  点击/评论:3167/0

卿勇  副教授(硕士生导师) 

单位:四川大学华西药学院药理教研室 

通讯地址:成都市人民南路三段十七号四川大学华西药学院 

电话:( 028 ) 85502314

E-mail:qingyongxyxy@aliyun.com

教育经历

  2004/4 - 2008/3,日本京都大学,分子医学,博士

  2002/4 - 2004/3,日本京都工艺纤维大学,应用生物学,硕士       

  1986/9 - 1991/7,西南医科大学,医学学士

科研与学术工作经历:

  2011/12 - 至今,四川大学,华西药学院,副教授

  2008/4-2010/9,日本京都大学,医学研究科放射遗传学研究室,教务辅佐、COE研究员

研究方向

1.以DNA损伤修复为靶向的抗肿瘤药物开发研究

2.药物遗传毒性分子机制研究

主要研究课题

1. DNA修复缺陷系统的建立与抗肿瘤靶向药物研究(四川大学引进人才科研启动经费资助项目, 2012-2014, 负责人)

2. 基于UBC13缺失肿瘤细胞的Deltonin高特异毒性机制研究(国家自然科学基金,主研,批准号:81373431)

3.抗乙肝病毒核苷/核苷酸类似物遗传毒性分子机制研究


近年发表论文:

1. Ying Liu, Xiaohua Wu*, Xiaoqing Hu, Ziyuan Chen, Hao Liu, Shunichi Takeda,Yong Qing*,Multiple repair pathways mediate cellular tolerance to resveratrol-induced DNA damage,Toxicology in Vitro,2017,42: 130–138.

2. Lei Jiang, Xiaohua Wu, Fang He, Ying Liu, Xiaoqing Hu, Shunichi Takeda, Yong Qing*, Genetic Evidence for Genotoxic Effect of Entecavir, an Anti-Hepatitis B Virus Nucleotide Analog, PLoS ONE, 2016, 11(1): e0147440. 

3. Qingyi Tong, Yong Qing*, Yang Wu, Xiaojuan Hu, Lei Jiang, Xiaohua Wu*, Dioscin inhibits colon tumor growth and tumor angiogenesis through regulating VEGFR2 and AKT/MAPK signaling pathways, Toxicology and Applied Pharmacology, 2014, 281 (2): 166–173.

4. Xiaojuan Hu, Xiaohua Wu, Yunfei Huang, Qingyi Tong, Shunichi Takeda, Yong Qing*, Berberine induces double-strand DNA breaks in Rev3 deficient cells, Molecular Medicine Reports, 2014; 9(5): 1883-1888.

5. Qing-Yi Tong, Yang He, Qing-Bing Zhao, Yong Qing*, Wen Huang*, Xiao-Hua Wu*, Cytotoxicity and apoptosis-inducing effect of steroidal saponins from Dioscorea zingiberensis Wright against cancer cells, Steroids, 2012, 77(12): 1219–1227.

6. Yi Li, Zhen-ling Wang, Fang He, Yang Wu, Wen Huang, Yang He, Qing-yi Tong, Yu-quan Wei, Yong Qing*, Li Yang* and Xiaohua Wu*, TP-58, a Novel Thienopyridine Derivative, Protects Mice from ConcanavalinA-Induced Hepatitis by Suppressing Inflammation, Cellular Physiology and Biochemistry, 2012, 29(1-2): 31-40.

7. Yong Qing#, Mitsuyoshi Yamazoe#, Kouji Hirota, Donniphat Dejsuphong, Wataru Sakai, Kimiyo N. Yamamoto, Douglas K. Bishop, XiaoHua Wu, Shunichi Takeda, The Epistatic Relationship between BRCA2 and the Other RAD51 Mediators in Homologous Recombination,  PLoS Genetics , 2011, 7(7): e1002148. 

8. Dan Shu#, Yong Qing#, Qingyi Tong, Yang He, Zhihua Xing, Yinglan Zhao, Yi Li, Yuquan Wei, Wen Huang, Xiaohua Wu, Deltonin Isolated from Dioscorea zingiberensis Inhibits Cancer Cell Growth through Inducing Mitochondrial Apoptosis and Suppressing Akt and Mitogen Activated Protein kinase Signals, Biological & Pharmaceutical Bulletin, 2011, 34(8) : 1231–1239.

9. Qing-Yi Tong#, Yong Qing#, Dan Shu, Yang He, Ying-Lan Zhao, Yi Li, Zhen-Ling Wang, Shi-Yuan Zhang, Zhi-hua Xing, Cheng Xu, Yu-Quan Wei, Wen Huang and Xiao-Hua Wu, Deltonin, a Steroidal Saponin, Inhibits Colon Cancer Cell Growth in Vitro and Tumor Growth in Vivo via Induction of Apoptosis and Antiangiogenesis, Cellular Physiology And Biochemistry, 2011, 27(3-4): 233-242.

10. Yoshimasa Takizawa#, Yong Qing#, Motoki Takaku, Takako Ishida, Yuichi Morozumi, Takashi Tsujita, Toshiaki Kogame, Kouji Hirota, Masayuki Takahashi, Takehiko Shibata, Hitoshi Kurumizaka and Shunichi Takeda, GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination, Nucleic Acids Research, 2010, 38(15): 5059–5074.




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