今天是:2017年11月19日 星期日 农历十月初二
詹先成 教授 (博士生导师)
作者:佚名  来源:  发布时间:2016年03月07日  点击/评论:11857/0

詹先成 教授 (博士生导师)

单 位:四川大学华西药学院物理化学教研室

通讯地址:成都市人民南路三段十七号四川大学华西药学院

电话: 13618091154

电子邮件: xczhan@mail.sc.cninfo.net

简历

1974~1977 四川医学院药学系化学制药专业

1980~1983 四川医学院药学系药剂学硕士研究生

1986~1988 美国德州医学中心 Baylor College of Medicine 访问学者

1977~四川医学院药学系 , 华西医科大学药学院任助教、讲师、副教授、教授、博士生导师、物理化学教研室主任

兼职:《药学学报》编委

研究方向

药物稳定性及物理药学

主要研究课题及成果

1. 程序变湿变温药物稳定性试验理论及方法的深入研究。(国家自然科学基金 2006 - 2008 )

2. 药物对氧稳定性试验的理论及方法研究。(国家自然科学基金 2005 - 2007 )

3. 固体药物对湿度稳定性试验的理论及方法研究。(国家自然科学基金 2002 - 2004 )

4. 药物对光稳定性试验的理论及方法研究。(国家自然科学基金 1998 - 2000 )

5. 药物稳定性加速试验的理论及方法研究。(国家自然科学基金 1995 - 1997 )

获奖

1. 药物稳定性试验的理论及方法研究。 国家教委科技进步奖 ( 甲类二等奖 ) 1997.3 。

2. 指数程序升温药物稳定性试验和程序升降温药物稳定性试验。 四川省科技进步奖 ( 三等奖 ) 1998 。

代表论著

1. New heating controller and computation for linear heating stability experiment. International Journal of Pharma- ceutics 1995;115:161~166 ,第一作者,通讯联系人

2. Computer-controlled heating system and new computation for recip-rocal heating stability experiment. Internatio- nal Journal of Pharmaceutics 1995;115:167~173 ,第一作者,通讯联系人

3. Kinetic study on the photostability of solid vesnarinone and the equivalent relationship between daylight and lamplight. Journal of Pharmaceutical Sciences 1995;84(5):624~626 ,第一作者,通讯联系人

4. Xiancheng Zhan*, Jinyou Jiang, Baozhong Ma, Gongkuan Yin. A Computer-controlled temperature recording system and a new computation for flexible heating stability experiments. Interna-tional Journal of Pharmaceutics 1995;126:29~34 ,第一作者,通讯联系人

5. Exponential heating in drug stability experiment and statistical evaluation of nonisothermal and isothermal pre- diction. Journal of Pharmaceutical Sciences 1997;86(6):709~715 ,第一作者,通讯联系人

6. Determination of rate order for degradation of drugs with nonisothermal stability experiment. Journal of Pharma- ceutical Sciences 1997;86(10):1099~1104 ,第一作者,通讯联系人

7. Cumulative illuminometer and shelf life of drugs in daylight indoors. Interna-tional Journal of Pharmaceutics 1998; 167(1~2):7~11 ,第一作者,通讯联系人

8. Improved stability of 25% vitamin C parenteral formulation. International Journal of Pharmaceutics 1998; 173(1~2):43~49 ,第一作者,通讯联系人

9. Influence of light and heat on the stability of rotundine sulfate injection. Journal of Pharmaceutical Sciences . 2001;90(10):1497~1504 ,第二作者,通讯联系人

10. Highly accurate nephelometric titrimetry. Journal of Pharmaceutical Sciences . 2004; 93(2): 441~448 ,第一作者

11. Ning He, Xiancheng Zhan*, Chengrong Li, Tao Lin, Linli Li. Determination of norfloxacin by highly accurate neph- elometric titration. Journal of Pharmaceutical Sciences . 2005; 94(3 ): 540~546 ,第二作者,通讯联系人

12. Determination of Promethazine Hydrochloride and its preparations by Highly-accurate Nephelometric Titration. In- ternational Journal of Pharmaceutics . Date of Acceptance: May 23, 2005, 第二作者,通讯联系人

13. Programmed Humidifying in Drug Stability Experiments. Journal of Pharmaceutical Sciences , Date of Acceptance: June 4, 2005, 第二作者,通讯联系人

参编教材

《物理化学》十一五国家级规划教材 主编 高等教育出版社

《物理化学》卫生部规划教材第三、四、五版,化学动力学章,第五版副主编。

《物理化学》(化学动力学章),殷恭宽主编,北京医科大学,中国协和医科大学联合出版社。

 

Profossor Xiancheng Zhan

Recent research interests:

Kinetic Studies on Drug Stability.

Main Publications

1. Qiang Zhao, Xiancheng Zhan*, Linli Li, Chengrong Li, Tao Lin, Xiaodong Yin, Ning He. Programmed Humidifying in Drug Stability Experiments. Journal of Pharmaceutical Sciences. 2005;94(11):2531~2540.

2. Ning He, Xiancheng Zhan *, Chengrong Li, Tao Lin, Linli Li. Determination of norfloxacin by highly accurate nephelometric titration. Journal of Pharmaceutical Sciences. 2005; 94(3):540~546.

3. Xiancheng Zhan, Chengrong Li*, Zhiyi Li, Xiucen Yang, Shuguang Zhong, Tao Yi. Highly Accurate Nephelometric Titrimetry. Journal of Pharmaceutical Sciences. 2004; 93(2): 441~448.

4. Linli Li, Xiancheng Zhan*, Kailan Li, Xiucen Yang. Influence of light and heat on the stability of rotundine sulfate injection. Journal of Pharmaceutical Sciences. 2001; 90(10):1497~1504.

5. Xiancheng Zhan*, Gongkuan Yin, Baozhong Ma. Determination of rate order for degradation of drugs with nonisothermal stability experiment Journal of Pharmaceutical Sciences 1997;86(10):1099~1104.

6. Xiancheng Zhan*, Gongkuan Yin, Lihua Wang, Baozhong Ma. Exponential heating in drug stability experiment and statistical evaluation of nonisothermal and isothermal prediction. Journal of Pharmaceutical Sciences 1997;86(6):709~715.

7. Xiancheng Zhan*, Gongkuan Yin, Shicheng Liu. Kinetic study on the photostability of solid vesnarinone and the equivalent relationship between daylight and lamplight. Journal of Pharmaceutical Sciences 1995;84(5):624~626.

8. Qi Zhang, Xiancheng Zhan*, Chengrong Li, Tao Lin, Linli Li, Xiaodong Yin, Ning He, Yan Shi. Determination of Promethazine Hydrochloride and its preparations by Highly-accurate Nephelometric Titration. International Journal of Pharmaceutics. 2005;302(1~2):10~17.

9. Xiancheng Zhan*, Gongkuan Yin, and Baozhong Ma. Improved stability of 25% vitamin C parenteral formulation. International Journal of Pharmaceutics 1998; 173(1-2):43-49.

10. Xiancheng Zhan*, Zhihong Deng, Gongkuan Yin, and Baozhong Ma. Cumulative illuminometer and shelf life of drugs in daylight indoors. Interna?tional Journal of Pharmaceutics 1998; 167(1-2):7-11.

11. Xiancheng Zhan*, Jinyou Jiang, Baozhong Ma, Gongkuan Yin. A Computer-controlled temperature recording system and a new computation for flexible heating stability experiments. Interna?tional Journal of Pharmaceutics 1995;126:29~34.

12. Xiancheng Zhan*, Jinyou Jiang, Shicheng Liu, Gongkuan Yin. Computer-controlled heating system and new computation for recip?rocal heating stability experiment. International Journal of Pharmaceutics 1995;115:167~173.

13. Xiancheng Zhan*, Gongkuan Yin, Baozhong Ma. New heating controller and computation for linear heating stability experiment. International Journal of Pharmaceutics 1995;115:161~166.

14. Yan Shi, Xiancheng Zhan,* Lie Ma, Bing Lin, Linli Li, Chengrong Li, Ning He. Compressed Oxygen in Drug Stability Experiments. Chem. Pharm. Bull., 2007; 55(1) 87~91.

15. Tao YI, Xian-Cheng ZHAN*, Cheng-Rong LI, Ning HE. Determination of Phenytoin Sodium Injection and Tablets by Highly Accurate Nephelometric Titration. Chem. Pharm. Bull., 2006;54(3):384-386.

16. Bing Lin, Xian-Cheng Zhan*, Lin-Li Li, Cheng-Rong Li, Hai-Jun Qi, and Jian-Lin Tao.Step nonisothermal method in kinetics studies of captopril oxdation under compressed oxygon. Yakugaku Zasshi, 2008;128(4):617~624.

17. Lin-Li Li*, Xian-Cheng Zhan*, Jian-Lin Tao, Evaluation of the Stability of Aspirin in Solid State by the Programmed Humidifying and Non-isothermal Experiments. Archives of Pharmacal Research, 2008;31(3):381~389.

18. Lin Tao, Zhan Xiancheng*, Yang Xiucen, He Ning, Li Chengrong, Li LinLi, Influence of illuminance on the Observed Order of Reaction of Photodegradation of Nitrofurazone Solution. Chinese Journal of Chemistry, 2005;23(8):1090~1094.

19. LI, Zhi-Yi ZHAN, Xian-Cheng*, LI, Lin-Li LI, Kai-Lan YANG, Xiu-Cen LIN, Tao LI, Cheng-Rong. Influence of Light and Heat on the Stability of Nitrofurazone Solution. Chinese Journal of Chemistry, 2005;23(7):918~924.

20. Lin Tao, Zhan Xian-cheng*, Li Kai-lan, Li Cheng-rong, Influence of light and temperature on the stability of procaine hydrochloride injection, Acta Pharmaceutica Sinica, 2004;39(8):645~649.

21. SHI Yan, ZHAN Xiancheng, MA Lie, LI Linli, LI Chengrong. Evaluation of antioxidants using oxidation reaction rate Constants. Front. Chem. China 2007, 2(2): 140–145.

 



  编辑:四川大学华西药学院
相关新闻
 
    CopyRight © 2005-2017 四川大学华西药学院 版权所有
    地址:四川省成都市人民南路三段17号  联系电话:028-85501628  传真:028-85501628  邮编:610041  邮箱:xyxban@163.com