简历

2000 – 2004年 四川大学华西药学院，理学学士

2004 – 2007年 四川大学华西药学院，理学硕士，导师：张志荣教授

2007 – 2012年 美国威斯康辛大学-麦迪逊分校药学院，PhD，导师：W. John Kao教授

2012 – 2014年 美国威斯康辛大学-麦迪逊分校生物医学工程系，从事博士后研究

2014年3月至今    四川大学华西药学院药剂学系，副教授 博士生导师                       

                                四川省第十三批学术和技术带头人后备人选                                                     

 

主要研究方向：新型生物材料用于皮肤创口敷料、靶向和长效缓控药物递释的研究；生物物理因素对纳米递药载体细胞内化行为的影响及相关机制研究。在Biomaterials, Acta Pharm Sin B, J. Control Rel, ACS AMI, J Nanobiotechnology,等本领域权威杂志发表一作及通讯作者论文30余篇。申请并获授权美国发明专利1项；申请并获授权中国发明专利1项；参编英文专著2本。主持国家自然科学基金项目2项，参与国家自然科学基金重大项目1项，参与科技部重大研究计划1项。担任《亚洲药剂学杂志》和《沈阳药科大学学报》青年编委。

 

近五年发表的文章

1. Huang DD, Gui JJ, Chen X, Yu RL, Gong T, Zhang ZR, Fu Y*. ACS Appl Mater Interfaces. 2022, 14, 46, 51776-51789.

2. Qin S^#, Wu BB^#, Gong T, Zhang ZR, Fu Y*. Targeted delivery via albumin corona nanocomplex to renal tubules to alleviate acute kidney injury. J Control Rel. 2022, 349, 401-412. (^#co-first authors)

3. Deng L, Fu Y*. Seeing is believing: time-lapse macro-imaging of Morphological Changes of Solid Dosages as a Teaching and Research Tool. Pharm Res. 2022, 39(5), 1019-1024. (Front cover)

4. Chen X, Zhang YX, Fu Y*. The critical  role of toll-like receptor-mediated signaling in cancer immunotherapy. Medicine in Drug Discovery. 2022, 14, 100122.

5. He SQ^#, Gui JJ^#, Xiong K, Gao HL*, Fu Y*. A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases. J Nanobiotech. 2022, 20, 101. (^#co-first authors)

6. Wang M, Wang SY, Pan Y, Yu RL, Zhang ZR, Fu Y*. In situ gel implant for postsurgical wound management and extended chemoimmunotherapy against breast cancer recurrence. Acta Biomaterialia. 2022, 138, 168-181.

7. Xu YY, Niu YN, Wu BB, Cao X, Gong T, Zhang ZR, Fu Y*. Extended-release of therapeutic microRNA via a host-guest supramolecular hydrogel to locally alleviate renal interstitial fibrosis. Biomaterial. 2021, 275, 120902.

8. Qin XY, Xu YY, Zhou X, Gong T, Zhang ZR, Fu Y*. An injectable micelle-hydrogel hybrid for localized and prolonged drug delivery in the management of renal fibrosis. Acta Pharm Sin B. 2021, 11(3), 835-847.

9. Wang SY, Liu RH, Fu Y*, Kao WJ*. Release Mechanisms and Applications of Drug Delivery Systems for Extended-Release. Exp Opin Drug Deliv. 2020, 17(9), 1289-1304.

10. Chen X, Wang M, Hu Y, Gong T, Zhang ZR, Yu RL, Fu Y*. Low-dose paclitaxel via hyaluronan functionalized bovine serum albumin nanoparticulate assembly for metastatic melanoma treatment. J Mater Chem B. 2020, 8(10), 2139-2147.

11. Xu YY^#, Qin S^#, Niu YN, Gong T, Zhang ZR, Fu Y*. Effect of fluid shear stress on the internalization of kidney-targeted delivery systems in renal tubular epithelial cells. Acta Pharm Sin B 2020, 10(4), 680-692. (^#co-first authors)

12. Hu Y, Chen X, Xu YY, Han XR, Wang M, Gong T, Zhang ZR, Kao WJ, Fu Y*. Hierarchical assembly of hyaluronan coated albumin nanoparticles for pancreatic cancer chemoimmunotherapy. Nanoscale. 2019,11(35),16476-16487.

13. Cao X, Hu Y, Luo S, Wang YJ, Gong T, Sun X, Fu Y*, Zhang ZR*. Neutrophil-mimicking therapeutic nanoparticles for targeted chemotherapy of pancreatic carcinoma. Acta Pharm Sin B. 2019, 9(3), 575-589.

14. Wang Y, Gong T, Zhang Z, Fu Y*. Matrix stiffness differentially regulates cellular uptake behavior of nanoparticles in two breast cancer cell lines. ACS Appl Mater Interfaces 2017, 9(31), 25915-25928.

 

书稿章节

Fu Y. “Co-delivery of anticancer therapeutics via lipid-based nanoscale delivery systems” Chapter in: Marlene Lúcio, Carla M. Lopes, Maria Elisabete C.D. Real Oliveira “Functional Lipid Nanosystems in Cancer”. Pan Stanford Publishing and CRC Press. 2022.

Fu Y, Kao WJ. Proteomic approaches to characterize surface-bound proteins and material-mediated cellular proteins. Proteins at Interfaces III: State of the Art Book series: ACS Symposium Series. Editors: T Horbett, J Brash, W Norde. 2012,1120,809-837.

 

 

Yao Fu PhD

 

ACADEMIC QUALIFICATIONS

Ph.D.    University of Wisconsin-Madison 2007 - 2012

              May 2012       Pharmaceutical Sciences Advisor: Dr. W. John Kao

M.S.      Sichuan University 2004 - 2007

              July 2007        Pharmaceutical Sciences Advisor: Dr. Zhirong Zhang

B.S.       Sichuan University 2000 – 2004                                                 

              July 2004        Pharmacy

 

PREVIOUS ACADEMIC POSITIONS HELD

Postdoctoral Research Associate, 9/2012 – 3/2014, Department of Biomedical Engineering (Co-advised by Dr. Pamela Kreeger and Dr. Kristyn Masters), University of Wisconsin-Madison

 

PRESENT ACADEMIC POSITIONS HELD

Associate Professor of Pharmaceutical Sciences, 3/2014 – now, West China School of Pharmacy, Sichuan University

 

SELECTED PUBLICATION

1. Huang DD, Gui JJ, Chen X, Yu RL, Gong T, Zhang ZR, Fu Y*. ACS Appl Mater Interfaces. 2022, 14, 46, 51776-51789.

2. Qin S^#, Wu BB^#, Gong T, Zhang ZR, Fu Y*. Targeted delivery via albumin corona nanocomplex to renal tubules to alleviate acute kidney injury. J Control Rel. 2022, 349, 401-412. (^#co-first authors)

3. Deng L, Fu Y*. Seeing is believing: time-lapse macro-imaging of Morphological Changes of Solid Dosages as a Teaching and Research Tool. Pharm Res. 2022, 39(5), 1019-1024. (Front cover)

4. Chen X, Zhang YX, Fu Y*. The critical  role of toll-like receptor-mediated signaling in cancer immunotherapy. Medicine in Drug Discovery. 2022, 14, 100122.

5. He SQ^#, Gui JJ^#, Xiong K, Gao HL*, Fu Y*. A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases. J Nanobiotech. 2022, 20, 101. (^#co-first authors)

6. Wang M, Wang SY, Pan Y, Yu RL, Zhang ZR, Fu Y*. In situ gel implant for postsurgical wound management and extended chemoimmunotherapy against breast cancer recurrence. Acta Biomaterialia. 2022, 138, 168-181.

7. Xu YY, Niu YN, Wu BB, Cao X, Gong T, Zhang ZR, Fu Y*. Extended-release of therapeutic microRNA via a host-guest supramolecular hydrogel to locally alleviate renal interstitial fibrosis. Biomaterial. 2021, 275, 120902.

8. Qin XY, Xu YY, Zhou X, Gong T, Zhang ZR, Fu Y*. An injectable micelle-hydrogel hybrid for localized and prolonged drug delivery in the management of renal fibrosis. Acta Pharm Sin B. 2021, 11(3), 835-847.

9. Wang SY, Liu RH, Fu Y*, Kao WJ*. Release Mechanisms and Applications of Drug Delivery Systems for Extended-Release. Exp Opin Drug Deliv. 2020, 17(9), 1289-1304.

10. Chen X, Wang M, Hu Y, Gong T, Zhang ZR, Yu RL, Fu Y*. Low-dose paclitaxel via hyaluronan functionalized bovine serum albumin nanoparticulate assembly for metastatic melanoma treatment. J Mater Chem B. 2020, 8(10), 2139-2147.

11. Xu YY^#, Qin S^#, Niu YN, Gong T, Zhang ZR, Fu Y*. Effect of fluid shear stress on the internalization of kidney-targeted delivery systems in renal tubular epithelial cells. Acta Pharm Sin B 2020, 10(4), 680-692. (^#co-first authors)

12. Hu Y, Chen X, Xu YY, Han XR, Wang M, Gong T, Zhang ZR, Kao WJ, Fu Y*. Hierarchical assembly of hyaluronan coated albumin nanoparticles for pancreatic cancer chemoimmunotherapy. Nanoscale. 2019,11(35),16476-16487.

13. Cao X, Hu Y, Luo S, Wang YJ, Gong T, Sun X, Fu Y*, Zhang ZR*. Neutrophil-mimicking therapeutic nanoparticles for targeted chemotherapy of pancreatic carcinoma. Acta Pharm Sin B. 2019, 9(3), 575-589.

14. Wang Y, Gong T, Zhang Z, Fu Y*. Matrix stiffness differentially regulates cellular uptake behavior of nanoparticles in two breast cancer cell lines. ACS Appl Mater Interfaces 2017, 9(31), 25915-25928.

 

Book chapters

Fu Y. “Co-delivery of anticancer therapeutics via lipid-based nanoscale delivery systems” Chapter in: Marlene Lúcio, Carla M. Lopes, Maria Elisabete C.D. Real Oliveira “Functional Lipid Nanosystems in Cancer”. Pan Stanford Publishing and CRC Press. 2022.

Fu Y, Kao WJ. Proteomic approaches to characterize surface-bound proteins and material-mediated cellular proteins. Proteins at Interfaces III: State of the Art Book series: ACS Symposium Series. Editors: T Horbett, J Brash, W Norde. 2012,1120,809-837.