程妍 副教授（硕士生导师）
通讯地址：成都市人民南路三段17号四川大学华西药学院（邮编610041）
电子邮箱:yancheng@scu.edu.cn
简历
2016/09-2018/09 斯坦福大学，医学院，访问学者
2012/09-至今 四川大学，华西药学院，教学科研
2009/04-2012/03京都大学，药学院，博士
2004/09-2007/06四川大学，华西药学院，硕士
2000/09-2004/07四川大学，华西药学院，学士
学术团体任职
1.中国医药生物技术协会药物分析技术分会委员会委员
2.中国药理学会分析药理学专业委员会委员
3.四川省色谱学会委员
4.Journal of Pharmaceutical Analysis青年编委
研究方向
1.药物靶标分析与新药筛选
2.生物医学影像分析与靶向探针（造影剂）研发
3.中药民族药（药材）质量控制与评价
主持的科研项目
1)国家自然科学基金青年基金（81402891）
2)教育部博士点新教师基金（20130181120114)
3）四川省卫生和计划生育委员会普及应用项目（16PJ225）
4）四川大学优秀青年学者基金（2015SCU04A37）
5）四川大学青年教师科研启动基金（2012SCU11091）
指导的学生科研项目
1）国家级大学生创新训练计划（201610610125）
2）四川省大学生创新训练计划（201510610327）
3）四川大学本科创新训练计划（201610611296）
4）四川大学本科创新训练计划（201510611139）
获奖情况
1）全国高等学校药学类专业青年教师微课教学大赛一等奖（药物分析组）
2）全国高等学校药学类专业青年教师教学能力大赛二等奖（药物分析组）
3）全国药物分析大会优秀论文优秀奖
4）全国药物分析大会优秀论文二等奖
5）四川大学青年骨干教师奖
6）四川大学基于智慧教学环境“探究式-小班化”教学质量优秀奖
7）四川大学华西药学院本科优秀教学奖
8）四川大学华西药学院本科优秀教学三等奖
9）四川大学本科优秀毕业论文（设计）三等奖（曹敏）（指导教师）
10）四川大学本科优秀毕业论文（设计）三等奖（曹思雨薇）（指导教师）
11）四川大学本科优秀毕业论文（设计）三等奖（李文君）（指导教师）
12）四川大学本科优秀毕业论文（设计）三等奖（朱必越）（指导教师）
13）四川大学本科优秀毕业论文（设计）三等奖（李雪）（指导教师）
14）四川大学本科优秀毕业论文（设计）三等奖（邓越）（指导教师）
代表性论著
1.Qinyu Wang,Jing Zhong,Kexin Li,Jiajun Wu,Xiaoxue Wang,Shen Jiang,Jiapei Dai,Yan Cheng*.Compact luminol chemiluminophores for in vivo detection and imaging of β-Sheet Protein Aggregates.Anal. Chem.2023,95, 1065-1073.
2.Biyue Zhu,Jing Yang,Richard Van,Fan Yang,Yue Yu,Astra Yu,Kathleen Ran,Keyi Yin,Yingxia Liang,Xunuo Shen,Wei Yin,Se Hoon Choi,Ying Lu,Changning Wang,Yihan Shao,Liang Shi,Rudolph E Tanzi,Can Zhang*,Yan Cheng*,Zhirong Zhang,Chongzhao Ran*.Epitope alteration by small molecules and applications in drug discovery.Chem. Sci.2022, 13, 8104-8116.
3.Jing Ma,Xiaoxue Wang,Na Li,Yan Cheng*.A bifunctional probe that allows dual-channel fluorescence turn-on detection of protein aggregates and hydrogen peroxide in neurodegenerative diseases.Sens. Actuators B Chem.2021,346,130536.
4.Wanyun Li, Jing Ma, Qian Jiang, Ting Zhang, Qingrong Qi*,Yan Cheng*.Fast Noninvasive Measurement of Brown Adipose Tissue in Living Mice by Near-Infrared Fluorescence and Photoacoustic Imaging.Anal. Chem.2020, 92(5), 3787-3794.
5.BiyueZhu,TingZhang,QianJiang, Ying Li, Yu Fu, Jiapei Dai, Ge Li, Qingrong Qi*,Yan Cheng*. Synthesis and evaluation of pyrazine and quinoxaline fluorophores for in vivo detection of cerebral tau tangles in Alzheimer’s models.Chem. Commun. (Camb).2018, 54(82), 11558-11561.
6.Zhu BY,Cheng Y*,Li GB,Yang SY,Zhang ZR*. Synthesis and evaluation of styrylpyran fluorophores for noninvasive detection of cerebral β-amyloid deposits.Bioorg Med Chem.2016 Feb 15;24(4):827-34.
7.YanCheng*,BiyueZhu,YueDeng,ZhirongZhang*.In vivo detection of cerebral amyloid fibrils with smart dicynomethylene-4H-pyran-based fluorescence probe.Anal. Chem.2015, 87(9), 4781-4787.
8.Cheng Y,*Zhu BY,Li X,Li GB,Yang SY,Zhang ZR*.Bioorg. Med. Chem. Lett.2015, 25(20):4472-6. doi: 10.1016/j.bmcl.2015.08.081.
9.MasahiroOno*,YanCheng, HiroyukiKimura, HiroyukiWatanabe, KenjiMatsumura, MasashiYoshimura, ShimpeiIikuni, YokoOkamoto, MasafumiIhara, RyosukeTakahashi, HideoSaji.Development of Novel (123)I-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of β-Amyloid Plaques in Alzheimer's Disease.PLoS One.，8(9):e74104, 2013.
10.Yan Cheng, Masahiro Ono*, Hiroyuki Kimura, Masashi Ueda, Hideo Saji.Technetium-99m Labeled Pyridyl Benzofuran Derivatives as Single Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Alzheimer’s Brains.J. Med. Chem.55(5), 2279-2286, 2012
11.Masahiro Ono*,Yan Cheng, Hiroyuki Kimura, Mengchao Cui, Shinya Kagawa, Ryuichi Nishii, Hideo Saji*.Novel18F-Labeled Benzofuran Derivatives with Improved Properties for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques in Alzheimer's Brains.J. Med. Chem.54(8), 2971-2979, 2011
12.Yan Cheng, Masahiro Ono*, Hiroyuki Kimura, Shinya Kagawa, Ryuichi Nishii, Hideo Saji*.Fluorinated Benzofuran Derivatives for PET Imaging of β-Amyloid Plaques in Alzheimer's Disease Brains.ACS Med. Chem. Lett.1(7), 321-325, 2010
13.Yan Cheng, Masahiro Ono*, Hiroyuki Kimura, Shinya Kagawa, Ryuichi Nishii, Hideo Saji*.A Novel18F-Labeled Pyridyl Benzofuran Derivative for Imaging of β-Amyloid Plaques in Alzheimer's Brains.Bioorg. Med. Chem. Lett.20(20), 6141–6144, 2010
14.Masahiro Ono*, Manami Ishikawa, Hiroyuki Kimura, Shun Hayashi, Kenji Matsumura, Hiroyuki Watanabe, Yoichi Shimizu,Yan Cheng, Mengchao Cui, Hidekazu Kawashima, Hideo Saji*,Development of Dual Functional SPECT/Fluorescent Probes for Imaging Cerebral β-amyloid Plaques.Bioorg. Med. Chem. Lett.20(13), 3885–3888, 2010
15.Masahiro Ono*, Rumi Watanabe, Hidekazu Kawashima,Yan Cheng, Hiroyuki Kimura, Hiroyuki Watanabe,Mamoru Haratake, Hideo Saji, Morio Nakayama*,Fluoro-pegylated Chalcones as Positron Emission Tomography Probes for in vivo Imaging of β-amyloid Plaques in Alzheimer's Disease.J. Med. Chem.52(20), 6394–6401, 2009.
