符垚 教授
单位：四川大学华西药学院药剂学系
地址：成都市人民南路三段17号四川大学华西药学院 610041
Email: yfu4@scu.edu.cn
简历
2000 – 2004年 四川大学华西药学院，理学学士
2004 – 2007年 四川大学华西药学院，理学硕士，导师：张志荣教授
2007 – 2012年 美国威斯康辛大学-麦迪逊分校药学院，PhD，导师：W. John Kao教授
2012 – 2014年 美国威斯康辛大学-麦迪逊分校生物医学工程系，从事博士后研究
2014年3月 – 2022年9月 四川大学华西药学院药剂学系，特聘副研究员/副教授
2022年9月至今 四川大学华西药学院药剂学系，教授 博士生导师
主要研究方向：新型生物材料用于皮肤创口敷料、靶向和长效缓控药物递释的研究；生物物理因素对纳米递药载体细胞内化行为的影响及相关机制研究。在Biomaterials, Acta Pharm Sin B, J. Control Rel, ACS AMI, J Nanobiotechnology,等本领域权威杂志发表一作及通讯作者论文40余篇。申请并获授权美国发明专利1项；申请并获授权中国发明专利1项；参编英文专著2本。主持国家自然科学基金项目2项，参与国家自然科学基金重大项目1项，参与科技部重大研究计划1项。担任《亚洲药剂学杂志》和《沈阳药科大学学报》青年编委。四川省第十三批学术和技术带头人后备人选 。
近五年发表的文章
1. Li CR, Wang JR, Niu YN, Zhang HN, Ouyang HL, Zhang GW, Fu Y*. Baicalin nanocomplexes with an in situ-forming biomimetic gel implant for repair of calvarial bone defects via localized sclerostin inhibition. ACS Appl Mater Interfaces. 2023, 15(7)), 9044-9057.
2. Wang M#, Wang YJ#, Gong T, Zhang ZR, Fu Y*. TLR4 blockade using docosahexaenoic acid restores vulnerability of drug-tolerant tumor cells and prevents breast cancer metastasis and post-surgical relapse. ACS Bio & Med Chem Au. 2023, 3, 97-113. (#co-first authors)
3. Huang DD, Gui JJ, Chen X, Yu RL, Gong T, Zhang ZR, Fu Y*. ACS Appl Mater Interfaces. 2022, 14, 46, 51776-51789.
4. Qin S#, Wu BB#, Gong T, Zhang ZR, Fu Y*. Targeted delivery via albumin corona nanocomplex to renal tubules to alleviate acute kidney injury. J Control Rel. 2022, 349, 401-412. (#co-first authors)
5. Deng L, Fu Y*. Seeing is believing: time-lapse macro-imaging of Morphological Changes of Solid Dosages as a Teaching and Research Tool. Pharm Res. 2022, 39(5), 1019-1024. (Front cover)
6. Chen X, Zhang YX, Fu Y*. The critical role of toll-like receptor-mediated signaling in cancer immunotherapy. Medicine in Drug Discovery. 2022, 14, 100122.
7. He SQ#, Gui JJ#, Xiong K, Gao HL*, Fu Y*. A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases. J Nanobiotech. 2022, 20, 101. (#co-first authors)
8. Wang M, Wang SY, Pan Y, Yu RL, Zhang ZR, Fu Y*. In situ gel implant for postsurgical wound management and extended chemoimmunotherapy against breast cancer recurrence. Acta Biomaterialia. 2022, 138, 168-181.
9. Xu YY, Niu YN, Wu BB, Cao X, Gong T, Zhang ZR, Fu Y*. Extended-release of therapeutic microRNA via a host-guest supramolecular hydrogel to locally alleviate renal interstitial fibrosis. Biomaterial. 2021, 275, 120902.
10. Qin XY, Xu YY, Zhou X, Gong T, Zhang ZR, Fu Y*. An injectable micelle-hydrogel hybrid for localized and prolonged drug delivery in the management of renal fibrosis. Acta Pharm Sin B. 2021, 11(3), 835-847.
11. Wang SY, Liu RH, Fu Y*, Kao WJ*. Release Mechanisms and Applications of Drug Delivery Systems for Extended-Release. Exp Opin Drug Deliv. 2020, 17(9), 1289-1304.
12. Chen X, Wang M, Hu Y, Gong T, Zhang ZR, Yu RL, Fu Y*. Low-dose paclitaxel via hyaluronan functionalized bovine serum albumin nanoparticulate assembly for metastatic melanoma treatment. J Mater Chem B. 2020, 8(10), 2139-2147.
13. Xu YY#, Qin S#, Niu YN, Gong T, Zhang ZR, Fu Y*. Effect of fluid shear stress on the internalization of kidney-targeted delivery systems in renal tubular epithelial cells. Acta Pharm Sin B 2020, 10(4), 680-692. (#co-first authors)
14. Hu Y, Chen X, Xu YY, Han XR, Wang M, Gong T, Zhang ZR, Kao WJ, Fu Y*. Hierarchical assembly of hyaluronan coated albumin nanoparticles for pancreatic cancer chemoimmunotherapy. Nanoscale. 2019,11(35),16476-16487.
15. Cao X, Hu Y, Luo S, Wang YJ, Gong T, Sun X, Fu Y*, Zhang ZR*. Neutrophil-mimicking therapeutic nanoparticles for targeted chemotherapy of pancreatic carcinoma. Acta Pharm Sin B. 2019, 9(3), 575-589.
书稿章节
Fu Y. “Co-delivery of anticancer therapeutics via lipid-based nanoscale delivery systems” Chapter in: Marlene Lúcio, Carla M. Lopes, Maria Elisabete C.D. Real Oliveira “Functional Lipid Nanosystems in Cancer”. Pan Stanford Publishing and CRC Press. 2022.
Fu Y, Kao WJ. Proteomic approaches to characterize surface-bound proteins and material-mediated cellular proteins. Proteins at Interfaces III: State of the Art Book series: ACS Symposium Series. Editors: T Horbett, J Brash, W Norde. 2012,1120,809-837.
编辑：四川大学华西药学院
